Video of Holmes’ Tremor
 

Video of Holmes’ Tremor

Short Description

Holmes’ Tremor:

First identified by Gordon Holmes in 1904, Holmes’ tremor or rubral tremor designates a combination of rest, postural, and action tremors due to midbrain lesions in the vicinity of the red nucleus, with combined disruption of dopaminergic nigrostriatal and cerebellorubrothalamic tracts. This type of tremor is irregular and low frequency (below 4.5 Hz). Signs of ataxia and weakness may be present. Common causes include cerebrovascular accident and multiple sclerosis, with a possible delay of 2 weeks to 2 years in occurrence of lesions and tremor onset. Rehabilitation difficulties out of proportion to the motor deficit can be present. Case reports suggest that pharmacologic or neurosurgical intervention may help.

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Full Description

Holmes’ Tremor:

First identified by Gordon Holmes in 1904, Holmes’ tremor or rubral tremor designates a combination of rest, postural, and action tremors due to midbrain lesions in the vicinity of the red nucleus, with combined disruption of dopaminergic nigrostriatal and cerebellorubrothalamic tracts. This type of tremor is irregular and low frequency (below 4.5 Hz). Signs of ataxia and weakness may be present. Common causes include cerebrovascular accident and multiple sclerosis, with a possible delay of 2 weeks to 2 years in occurrence of lesions and tremor onset. Rehabilitation difficulties out of proportion to the motor deficit can be present. Case reports suggest that pharmacologic or neurosurgical intervention may help. 

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